The Oncofood venture revealed some expectations of most cancers sufferers relating to new meals options.
Most cancers is among the many main causes of loss of life worldwide. In accordance to the Global Cancer Observatory, in 2018 there have been 18.1 million new instances and 9.5 million cancer-related deaths worldwide.1
One of many fundamental challenges for most cancers sufferers present process therapy is stopping or mitigating malnutrition. Most cancers-related malnutrition is very prevalent in sufferers present process most cancers therapy, various from eight to 84 %, depending on most cancers web site and stage.2 Nevertheless, not all sufferers endure from malnutrition, however most expertise a discount of their every day meals consumption as they usually have adversarial uncomfortable side effects (eg, style loss, dangerous style in mouth, metallic style, sores in mouth, vomiting, lack of urge for food and dysphagia).3
Poor dietary standing throughout most cancers therapy weakens the affected person and makes the administration of an applicable therapy troublesome, resulting in an elevated size of hospital keep, decreased therapy tolerance and elevated therapy uncomfortable side effects.4 The prognosis for most cancers sufferers with weight reduction is worse than for weight-stable sufferers.
The present medical vitamin market gives totally different oral dietary assist merchandise, but these fail to handle the pleasure of consuming, or sufferers’ meals preferences.
Most cancers therapies’ uncomfortable side effects
Style and scent alterations are a well-recognised reason behind decreased meals consumption and are reported as being one of the crucial distressing uncomfortable side effects of most cancers therapy, together with fatigue, nausea, vomiting and hair loss. They’re regularly noticed in oncological sufferers present process each radiotherapy and chemotherapy.
Entry to quite a lot of engaging meals merchandise is restricted for oncological sufferers.
The self-reported alterations in most cancers sufferers present process chemotherapy are excessive, ranging between 45 and 84 % for adjustments in style, and differ based on the kind of most cancers and chemotherapy routine.5
Chemosensory alterations embrace a discount in scent and style sensitivity, an absence of style sensation (ageusia), and distortion of regular style (dysgeusia) or a style notion with out an exterior stimulus (phantogeusia).
Different medical situations equivalent to dysphagia, dry mouth, mucositis or nausea are additionally regularly skilled. Dysphagia is outlined as ‘any disruption within the swallowing course of throughout bolus transport from the oral cavity to the abdomen’ and is extra widespread for these with head and neck cancers. Most cancers progress, notably within the mouth, throat or oesophagus, might slender these passages and create swallowing difficulties.6
The present marketplace for oncological sufferers
Entry to quite a lot of engaging meals merchandise is restricted for oncological sufferers. The present medical vitamin market gives totally different choices for sufferers beneath threat of malnutrition, that are primarily meals dietary supplements or oral dietary assist merchandise. Oral dietary assist merchandise are used when sufferers are mildly malnourished or, conversely, are in good situation however are candidates for a probably poisonous oncological remedy. They are designed to handle sufferers’ dietary necessities and are normally high-energy-density merchandise added to meals. The vary of merchandise is kind of restricted, with milkshakes, soups, purees, or texture-modified merchandise being essentially the most consultant examples.
The medical vitamin market dimension was valued at round $33 billion in 2019 and is anticipated to expertise progress of over 5.3 % CAGR from 2020 to 2027.7 Some key components propelling the expansion of the market embrace the rising prevalence of metabolic problems, excessive spending on healthcare and the rise of center courses in rising economies.
There are main gamers within the medical vitamin market, however presently, no meals merchandise particularly focused at most cancers sufferers within the meals retail sector.
ONCOFOOD: a consumer-centred strategy
ONCOFOOD is an innovation venture funded by EIT Food (European Institute of Innovation and Technology, European Union) and consists of a consortium of European firms, universities and know-how centres (AZTI, College of Warsaw, College of Studying, Maspex and Pure Machines).
This venture proposes the design and improvement of a spread of latest meals options addressing dietary, sensorial and texture necessities to advertise the pleasure of consuming and forestall malnutrition in oncological sufferers. These options have been designed in consideration of sufferers’ opinions and examined for his or her acceptability by the goal group for the profitable improvement of tailor-made options.
“The analysis revealed that dietary composition is vital for most cancers sufferers and caregivers.
As product improvements usually fail because of the mismatch between product improvement and client expectations and desires, the venture was accompanied by a posh collection of client analysis actions. These included: (i) qualitative research to research sufferers’ meals limitations, wants and expectations in the direction of new meals merchandise and an preliminary evaluation of a set of latest product ideas; and (ii) quantitative research, the place developed prototypes have been examined by sufferers to judge their sensory traits and acceptability earlier than being launched to the market.
The qualitative examine was performed in three international locations (Spain, Poland and UK), by way of particular person in-depth interviews and focus group discussions, with a complete of 53 respondents together with sufferers, ex-patients, caregivers and healthcare professionals.
The analysis revealed that dietary composition is vital for most cancers sufferers and caregivers. They appear fastidiously on the record of elements of each product they purchase; specializing in these with no added sugar and which can be pure whereas remaining pleasurable. Meals turns into a part of the therapeutic course of and is perceived as medication.
Most cancers sufferers from all three international locations expressed their dissatisfaction with the present market providing. There may be an consciousness of the few merchandise obtainable, however these have been related to being unwell and in dangerous situation.
Sufferers want a wider vary of flavours, tastes and choices to select from; there’s a want for meals with a savoury style relatively than candy (presently obtainable in the marketplace).
Our findings additionally revealed that merchandise for oncological sufferers must be handy. Most sufferers and caregivers are normally absorbed by all of the uncomfortable side effects of the sickness on a affected person’s life and don’t have the time to arrange sophisticated meals. Meals must be simple to retailer and put together at any time; not just for use at
residence, but in addition for consuming on the go.
Merchandise that may be eaten with little preparation and in small handy packages, allow sufferers to expertise the social perform of meals, which may be restricted; for instance, they usually can’t eat what’s served in eating places or at different social occasions.
Contemplating the findings on the buyer research for most cancers sufferers, Polish-based meals firm, Maspex, proposed the event of fruit and vegetable snacks in pouch pack format. These usually are not a brand new answer, however the concept of setting optimum elements into a lightweight and sensible format is a novelty within the oncological area.
Maspex (through fruit juice firm Tymbark) has in depth expertise in and a large portfolio of these sorts of pouches for various age teams. For most cancers sufferers, the formulation have been tailored with particular dietary necessities (protein, carbohydrates, nutritional vitamins and minerals) and style wants in thoughts. These merchandise comprise greens, fruits, groats, oatmeal, rice and even yoghurt. The nice benefits of those are the pure origin of the elements, optimum dietary values and comfort, in addition to being microbiologically protected to eat.
Alternatively, for these sufferers experiencing dysphagia or needing a comfortable weight-reduction plan, Pure Machines proposed a spread of 3D-printed meals and snacks utilizing a number of puréed pure elements and recipes particularly tailored for dietary necessities and texturised for dysphagia (stage 4, IDDSI framework).
The corporate developed and manufactured an modern 3D meals printer named Foodini. Using the 3D food-printing know-how, and notably Foodini, offers additional advantages for each the healthcare professionals (in hospitals and healthcare centre environments) and the top‑consumer (affected person). Firstly, it affords a extra personalised answer tailored for every affected person’s wants. Secondly, in comparison with puréed meals, the 3D-printed meals gives the chance to separate totally different elements inside the dish, permitting the affected person to tell apart between totally different flavours launched in a number of layers. Thirdly, it improves the looks of meals, avoiding the monotonous puréed meals, which based mostly on the outcomes from our client evaluation, is a vital component and corresponding to style. In this case, the brand new 3D designs have been impressed, amongst others, by inventive designs such because the silhouette of Frida Kahlo’s face.
New modern meals options aimed toward these with most cancers should be designed contemplating not solely their dietary wants however their sensory necessities. They need to assist alleviate signs, forestall malnutrition and promote the pleasure of consuming, to assist encourage a greater high quality of life. Moreover, these merchandise must be tasty, pure and handy. One modern answer for these in want of texture-modified diets lies in 3D-printed meals.
- Globocan (2018). The International Most cancers Observatory (GCO) – IARC worldwide company for Analysis in Most cancers, WHO
- Stratton RJ, Inexperienced CJ, Elia M (2004). Illness-Associated Malnutrition: An-Based mostly Strategy To Remedy. CAB Worldwide, Wallingford, UK
- Cohen J, Wakefield CE, Laing DG (2016). Scent and style problems ensuing from most cancers and chemotherapy. Curr PharmDes, 22:2253–2263
- Bozzetti F. (2013). Dietary assist of the oncology affected person. Crit Rev Oncol/Hematol, 87:172–200
- Amézaga J, Alfaro B, Ríos Y, Larraioz A, Ugartemendia G, Urruticoechea A, Tueros I. (2018). Assessing style and scent alterations in most cancers sufferers present process chemotherapy based on therapy. Assist Care Most cancers, 26(12):4077-4086
- Gaziano JE. (2002). Analysis and administration of oropharyngeal Dysphagia in head and neck most cancers. Most cancers Management, 9(5):400-409
- International Medical Diet Market Dimension examine, by Route of Administration (Oral, Enteral, Parenteral), by Software (Most cancers, Neurological Ailments, Gastrointestinal Issues, Metabolic Issues, Others), by Finish-Consumer (Pediatric, Adults, Geriatric) and Regional Forecasts 2020-2027. Report ID: MSR2854734, July 30, 2020